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CAS 59382-59-1

methyl 2-methyl-3-nitrobenzoate

CodesLENA-001

Application context (from source-drug indications)

边缘带B细胞淋巴瘤来那度胺滤泡性淋巴瘤来那度胺成人T细胞白血病淋巴瘤来那度胺套细胞淋巴瘤来那度胺骨髓增生异常综合征来那度胺多发性骨髓瘤来那度胺

Source drugs (routes using this intermediate)

DrugTierExpiry
来那度胺LenalidomideTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

来那度胺原研路线steps: 5total yield: 0.46 g
methyl 2-methyl-3-nitrobenzoate1-bromopyrrolidine-2,5-dionemethyl 2-(bromomethyl)-3-nitrobenzoate(tert-butoxycarbonyl)-L-glutamine(R)-2-((tert-butoxycarbonyl)amino)-5-(4-nitro-1-oxoisoindolin-2-yl)-5-oxopentanoic acid(R)-2-amino-5-(4-nitro-1-oxoisoindolin-2-yl)-5-oxopentanoic acid3-(4-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Intermediates available on this site

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SupplierProductPrice bandMOQLead timeQualifications
Qualified Partner — East China API Worksmethyl 2-(bromomethyl)-3-nitrobenzoate
Pharmaceutical Intermediates
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Unibest Nantong cGMP Site3-aminopiperidine-2,6-dione hydrochloride
Pharmaceutical Intermediates
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