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CAS 128-08-5
1-bromopyrrolidine-2,5-dione
Codes：ALPE-015、LENA-002
Application context (from source-drug indications)
生长障碍阿吡利塞遗传病阿吡利塞PIK3CA相关生长过度谱系阿吡利塞乳腺癌阿吡利塞边缘带B细胞淋巴瘤来那度胺滤泡性淋巴瘤来那度胺成人T细胞白血病淋巴瘤来那度胺套细胞淋巴瘤来那度胺骨髓增生异常综合征来那度胺多发性骨髓瘤来那度胺
Source drugs (routes using this intermediate)
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine→(S)-pyrrolidine-2-carboxamide→4-methyl-2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine→N-methoxy-N-methylacetamide→1-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)propan-2-one→1-bromopyrrolidine-2,5-dione→4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine hydrobromide→phenyl (4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)carbamate
methyl 2-methyl-3-nitrobenzoate→1-bromopyrrolidine-2,5-dione→methyl 2-(bromomethyl)-3-nitrobenzoate→(tert-butoxycarbonyl)-L-glutamine→(R)-2-((tert-butoxycarbonyl)amino)-5-(4-nitro-1-oxoisoindolin-2-yl)-5-oxopentanoic acid→(R)-2-amino-5-(4-nitro-1-oxoisoindolin-2-yl)-5-oxopentanoic acid→3-(4-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | methyl 2-(bromomethyl)-3-nitrobenzoate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 3-aminopiperidine-2,6-dione hydrochloride Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.