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CAS 86728-85-0

Methyl (3S)-4-chloro-3-hydroxybutanoate

CodesAtorvastatin-163

Application context (from source-drug indications)

高脂血症阿托伐他汀锶蛛网膜下腔出血阿托伐他汀锶高血压阿托伐他汀锶

Source drugs (routes using this intermediate)

DrugTierExpiry
阿托伐他汀锶Atorvastatin strontiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

阿托伐他汀锶优化路线steps: 6total yield: 206.7g(Atorvastatin-161)
Methyl (3S)-4-chloro-3-hydroxybutanoateMethyl (3S)-4-chloro-3-[(trimethylsilyl)oxy]butanoate(3S)-4-Chloro-3-[(trimethylsilyl)oxy]butanaltert-Butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoatetert-Butyl [(4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate[(4S,6R)-6-[2-(tert-Butoxy)-2-oxoethyl]-2,2-dimethyl-1,3-dioxan-4-yl]methyl acetate1,1-Dimethylethyl acetate1-Methoxy-1-methylethyl methyl ether

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