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CAS 869478-10-4
6-(benzyloxy)-8-(2-chloroacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Codes:OLOD-012
Application context (from source-drug indications)
慢性阻塞性肺疾病盐酸奥达特罗慢性支气管炎盐酸奥达特罗气肿盐酸奥达特罗干眼症盐酸奥达特罗哮喘盐酸奥达特罗肝脏疾病盐酸奥达特罗
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 盐酸奥达特罗Olodaterol Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(5-(benzyloxy)-2-hydroxyphenyl)ethanone→1-(5-(benzyloxy)-2-hydroxy-3-nitrophenyl)ethanone→1-(3-amino-5-(benzyloxy)-2-hydroxyphenyl)ethanone→2-chloroacetyl chloride→8-acetyl-6-(benzyloxy)-2H-benzo[b][1,4]oxazin-3(4H)-one→1-(4-methoxyphenyl)-2-methylpropan-2-amine→6-(benzyloxy)-8-(2-chloroacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one→(R)-6-(benzyloxy)-8-(2-chloro-1-hydroxyethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one→(R)-6-(benzyloxy)-8-(oxiran-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one→(R)-6-(benzyloxy)-8-(1-hydroxy-2-((1-(4-methoxyphenyl)-2-methylpropan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
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