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CAS 917342-29-1
tert-butyl ((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)carbamate
Codes：CARI-020
Application context (from source-drug indications)
重度抑郁症卡利拉嗪盐酸盐精神分裂症卡利拉嗪盐酸盐躁狂症卡利拉嗪盐酸盐
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 卡利拉嗪盐酸盐Cariprazine Hydrochloride | Tier A — Act now | 2029 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate→1-(2,3-dichlorophenyl)piperazine→2-(4-nitrophenyl)acetic acid→ethyl 2-((1r,4r)-4-aminocyclohexyl)acetate hydrochloride→ethyl 2-((1r,4r)-4-((tert-butoxycarbonyl)amino)cyclohexyl)acetate→tert-butyl ((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)carbamate→(1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine→N-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1H-imidazole-1-carboxamide
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