卡利拉嗪盐酸盐
Tier A — Act nowCariprazine Hydrochloride · all drugs expiring in 2029 →
Targets：5-HT2A、5-HT1A、DRD2、DRD3、HRH1、5-HT2B
Brand：Vraylar、Reagila
Indications (approved)：重度抑郁症、精神分裂症、躁狂症
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| CARI-001 | 56961-77-4 | 1-bromo-2,3-dichlorobenzene |
| CARI-002 | 57260-71-6Available | tert-butyl piperazine-1-carboxylate |
| CARI-003 | 503315-03-5 | tert-butyl 4-(2,3-dichlorophenyl)piperazine-1-carboxylate |
| CARI-004 | 119532-26-2Available | 1-(2,3-dichlorophenyl)piperazine hydrochloride |
| CARI-005 | 215790-29-7 | tert-butyl ((1r,4r)-4-(2-oxoethyl)cyclohexyl)carbamate |
| CARI-006 | 506427-91-4 | tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate |
| CARI-007 | 791778-53-5 | (1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine |
| CARI-008 | 79-44-7 | dimethylcarbamic chloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| CARI-008 | 79-44-7 | dimethylcarbamic chloride |
| CARI-009 | 87976-86-1 | 4-aminocyclohexanone |
| CARI-010 | 1512029-27-4 | 1,1-dimethyl-3-(4-oxocyclohexyl)urea |
| CARI-011 | 867-13-0Available | ethyl 2-(diethoxyphosphoryl)acetate |
| CARI-012 | 1698050-47-3 | ethyl 2-(4-(3,3-dimethylureido)cyclohexylidene)acetate |
| CARI-013 | 1642586-63-7 | ethyl 2-((1r,4r)-4-(3,3-dimethylureido)cyclohexyl)acetate |
| CARI-014 | 1698050-40-6 | 3-((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)-1,1-dimethylurea |
| CARI-015 | 1642586-58-0 | 1,1-dimethyl-3-((1r,4r)-4-(2-oxoethyl)cyclohexyl)urea |
| CARI-016 | 41202-77-1Available | 1-(2,3-dichlorophenyl)piperazine |
| Code | CAS No. | Intermediate |
|---|---|---|
| CARI-006 | 506427-91-4 | tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate |
| CARI-016 | 41202-77-1Available | 1-(2,3-dichlorophenyl)piperazine |
| CARI-017 | 104-03-0 | 2-(4-nitrophenyl)acetic acid |
| CARI-018 | 113543-96-7 | ethyl 2-((1r,4r)-4-aminocyclohexyl)acetate hydrochloride |
| CARI-019 | 946598-34-1 | ethyl 2-((1r,4r)-4-((tert-butoxycarbonyl)amino)cyclohexyl)acetate |
| CARI-020 | 917342-29-1 | tert-butyl ((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)carbamate |
| CARI-021 | 791778-53-5 | (1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine |
| CARI-022 | 1702725-92-5 | N-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1H-imidazole-1-carboxamide |
Frequently asked questions
What are the approved indications of Cariprazine Hydrochloride?
Approved indications include: 重度抑郁症, 精神分裂症, 躁狂症.
When does the Cariprazine Hydrochloride patent expire?
Based on public sources, the Cariprazine Hydrochloride patent expires in 2029.
How many synthesis routes are recorded for Cariprazine Hydrochloride?
3 synthesis routes are recorded; the shortest is 5 steps with 0.83 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Cariprazine Hydrochloride intermediates?
4 intermediate CAS of Cariprazine Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Cariprazine Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24