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CAS 98-80-6
phenylboronic acid
Codes:PERAM-004、Sertraline Hydrochloride-129
Application context (from source-drug indications)
强直阵挛性癫痫吡仑帕奈癫痫部分性发作吡仑帕奈癫痫吡仑帕奈癫痫发作吡仑帕奈强迫性障碍枸橼酸舍曲林
Source drugs (routes using this intermediate)
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
5-bromopyridin-2-amine→5-bromo-3-iodopyridin-2-amine→5-bromo-3-iodopyridin-2(1H)-one→phenylboronic acid→5-bromo-3-iodo-1-phenylpyridin-2(1H)-one→2-(1,3,2-dioxaborinan-2-yl)benzonitrile→2-(5-bromo-2-oxo-1-phenyl-1,2-dihydropyridin-3-yl)benzonitrile→2-(2-oxo-1-phenyl-5-(tributylstannyl)-1,2-dihydropyridin-3-yl)benzonitrile→2-chloropyridine
phenylboronic acid→2-(1,3,2-dioxaborinan-2-yl)benzonitrile→2,5-dibromopyridine→5-bromo-2-methoxypyridine→2-(tributylstannyl)pyridine→6'-methoxy-2,3'-bipyridine→[2,3'-bipyridin]-6'(1'H)-one→5'-bromo-[2,3'-bipyridin]-6'(1'H)-one→5'-bromo-6'-methoxy-2,3'-bipyridine→2-(6'-methoxy-[2,3'-bipyridin]-5'-yl)benzonitrile→2-(6'-oxo-1',6'-dihydro-[2,3'-bipyridin]-5'-yl)benzonitrile
(2E)-3-(3,4-Dichlorophenyl)acrylaldehyde→1,1-Dimethylethyl isocyanide→(3E)-N-tert-Butyl-4-(3,4-dichlorophenyl)-2-oxobut-3-enamide→(4R)-N-tert-Butyl-4-(3,4-dichlorophenyl)-2-oxo-4-phenylbutanamide→(2Z,4R)-N-tert-Butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenylbutanamide→(4R)-N-tert-Butyl-4-(3,4-dichlorophenyl)-4-phenylbutanamide→N-tert-Butyl-2-[(2R)-2-(3,4-dichlorophenyl)-2-phenylethyl]-1,3-dithiolane-2-carboxamide→(4R)-4-(3,4-Dichlorophenyl)-4-phenylbutanoic acid→4(S)-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-one→1,3-Bis(bromanyl)benzene→(R)-S-tert-Butyl 2-methylpropane-2-sulfinothioate→1,3-Bis[(R)-tert-butylsulfinyl]benzene→Chlorodiphenylphosphane→Sertraline Hydrochloride-138→phenylboronic acid
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