← 返回专利悬崖列表
CAS 62-56-6
thioureaSulfoureaAminothiocarboxamide
登记编号：TICA-041、AVAN-026、AVAT-003、LUSU-007、FEBU-014、Cefoselis Sulfate-033、S-pantoprazole sodium-055
应用背景（按来源药适应症）
中风替格瑞洛急性冠脉综合征替格瑞洛心肌梗塞替格瑞洛外周血管疾病替格瑞洛勃起功能障碍阿伐那非血小板减少马来酸阿伐曲泊帕特发性血小板减少性紫癜马来酸阿伐曲泊帕肝脏疾病马来酸阿伐曲泊帕血小板减少芦曲泊帕高尿酸血症非布司他痛风非布司他颅内出血非布司他溃疡性结肠炎非布司他慢性肾功能不全非布司他疼痛非布司他细菌感染硫酸头孢噻利胃食管反流病（S）-泮托拉唑钠消化性溃疡（S）-泮托拉唑钠出血（S）-泮托拉唑钠创伤和损伤（S）-泮托拉唑钠昏迷（S）-泮托拉唑钠吸入性肺炎（S）-泮托拉唑钠
来源药（使用该中间体的合成路线）
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
4,6-dichloro-2-(propylthio)pyrimidin-5-amine→diethyl 2-acetamidomalonate→thiourea→sodium 5-acetamido-4,6-dihydroxypyrimidine-2-thiolate→N-(4,6-dihydroxy-2-mercaptopyrimidin-5-yl)acetamide→1-bromopropane→N-(4,6-dihydroxy-2-(propylthio)pyrimidin-5-yl)acetamide→5-amino-2-(propylthio)pyrimidine-4,6-diol hydrochloride
diethyl 2-(ethoxymethylene)malonate→(3-chloro-4-methoxyphenyl)methanamine hydrochloride→(S)-pyrrolidin-2-ylmethanol→pyrimidin-2-ylmethanamine→thiourea→AVAN-027→AVAN-028→AVAN-029→AVAN-030→AVAN-031→AVAN-032→AVAN-033
1-(4-chlorothiophen-2-yl)ethanone→2-bromo-1-(4-chlorothiophen-2-yl)ethanone→thiourea→4-(4-chlorothiophen-2-yl)thiazol-2-amine→1-cyclohexylpiperazine→4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine→5,6-dichloronicotinic acid→5,6-dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide→ethyl piperidine-4-carboxylate→ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate→maleic acid
1-(3-bromo-2-methoxyphenyl)ethanone→(S)-1-(3-bromo-2-methoxyphenyl)ethanol→1-iodohexane→(S)-1-bromo-3-(1-(hexyloxy)ethyl)-2-methoxybenzene→2-chloro-N-methoxy-N-methylacetamide→(S)-2-chloro-1-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)ethanone→thiourea→(S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine→(E)-3,5-dichloro-4-(3-ethoxy-2-methyl-3-oxoprop-1-en-1-yl)benzoic acid→(S,E)-ethyl 3-(2,6-dichloro-4-((4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-yl)carbamoyl)phenyl)-2-methylacrylate→3,5-dichloro-4-formylbenzoic acid→ethyl 2-(diethoxyphosphoryl)propanoate
ethyl 2-chloro-3-oxobutanoate→1-bromo-2-methylpropane→ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate→5-bromo-2-hydroxybenzaldehyde→5-bromo-2-isobutoxybenzaldehyde→5-bromo-2-isobutoxybenzonitrile→(3-cyano-4-isobutoxyphenyl)boronic acid→ethyl 2-bromo-4-methylthiazole-5-carboxylate→thiourea→ethyl 2-amino-4-methylthiazole-5-carboxylate
4-Chloro-2(Z)-(methoxyimino)-3-oxobutyric acid→5-amino-2-{[(6R,7R)-7-amino-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-(2-hydroxyethyl)-1H-pyrazol-2-ium→3-amino-1-{[(6R,7R)-2-carboxylato-7-[(2Z)-4-chloro-2-(methoxyimino)-3-oxobutanamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-2-(2-hydroxyethyl)-2H-pyrazol-1-ium→Sulfourea→(6R,7R)-3-[[5-Amino-1-(2-hydroxyethyl)-1H-pyrazol-2-ium-2-yl]methyl]-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→Aminothiocarboxamide→(3,4-Dimethoxypyridin-2-yl)methyl hydrosulfide→Chloridocarbonic acid ethyl ester→Ethyl (3,4-dimethoxy-2-pyridyl)methylsulfanylformate→1,2-Diamino-4-(difluoromethoxy)benzene→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfinyl)-1H-benzimidazole
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。