← 返回专利悬崖列表
CAS 808115-50-6
methyl 2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetate
登记编号：ROXA-004
应用背景（按来源药适应症）
贫血罗沙司他
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 罗沙司他Roxadustat | Tier C · 观察 / 贸易 | 2028 |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
4-phenoxyphthalic acid→2-aminoacetic acid→2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetic acid→methyl 2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetate→butyl 1,4-dihydroxy-7-phenoxyisoquinoline-3-carboxylate→butyl 1-bromo-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate→1-bromo-4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid→benzyl 4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxylate→4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid→benzyl 2-aminoacetate hydrochloride→benzyl 2-(4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | Methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | 5-Phenoxyisobenzofuran-1(3H)-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid ethyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。