Adefovir Dipivoxil
Tier C — Watch / tradeAdefovir Dipivoxil
Targets：RT, HBV pol
Brand：Preveon (former TM), YouHeDing, Hepsera
Indications (approved)：Hepatitis B
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ADEF-001 | 106941-25-7 | ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid |
| ADEF-002 | 18997-19-8 | chloromethyl pivalate |
| Code | CAS No. | Intermediate |
|---|---|---|
| ADEF-001 | 106941-25-7 | ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid |
| ADEF-002 | 18997-19-8 | chloromethyl pivalate |
| ADEF-003 | 73-24-5 | 9H-purin-6-amine |
| ADEF-004 | 96-49-1 | 1,3-dioxolan-2-one |
| ADEF-005 | 707-99-3 | 2-(6-amino-9H-purin-9-yl)ethan-1-ol |
| ADEF-006 | 31618-90-3 | (diethoxyphosphoryl)methyl 4-methylbenzenesulfonate |
| ADEF-007 | 116384-53-3 | diethyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate |
| Code | CAS No. | Intermediate |
|---|---|---|
| ADEF-001 | 106941-25-7 | ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid |
| ADEF-002 | 18997-19-8 | chloromethyl pivalate |
| ADEF-003 | 73-24-5 | 9H-purin-6-amine |
| ADEF-008 | 116384-56-6 | diethyl ((2-chloroethoxy)methyl)phosphonate |
Frequently asked questions
What are the approved indications of Adefovir Dipivoxil?
Approved indications include: Hepatitis B.
When does the Adefovir Dipivoxil patent expire?
No public expiry year is available for Adefovir Dipivoxil yet; this page updates once verified.
How many synthesis routes are recorded for Adefovir Dipivoxil?
3 synthesis routes are recorded; the shortest is 1 steps with 0.59 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Adefovir Dipivoxil intermediates?
All intermediates in Adefovir Dipivoxil routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Adefovir Dipivoxil intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-27