Clazosentan Sodium
Tier C — Watch / tradeClazosentan Sodium
Targets：ETAR
Brand：Pivlaz
Indications (approved)：动脉瘤, Intracranial vasospasm, Subarachnoid haemorrhage, Cerebral infarction, 脑缺血
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| CLAZ-001 | 100-48-1 | isonicotinonitrile |
| CLAZ-002 | 6345-27-3 | isonicotinimidamide hydrochloride |
| CLAZ-003 | 150726-89-9 | dimethyl 2-(2-methoxyphenoxy)malonate |
| CLAZ-004 | 150728-08-8 | 5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidine-4,6-diol |
| CLAZ-005 | 150727-72-3 | 4,6-dichloro-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidine |
| CLAZ-006 | 180385-16-4 | 4-(4,6-dichloro-5-(2-methoxyphenoxy)pyrimidin-2-yl)pyridine 1-oxide |
| CLAZ-007 | 197448-77-4 | potassium ((5-methylpyridin-2-yl)sulfonyl)amide |
| CLAZ-008 | 180385-42-6 | 4-(4-chloro-5-(2-methoxyphenoxy)-6-((5-methylpyridine)-2-sulfonamido)pyrimidin-2-yl)pyridine 1-oxide |
| CLAZ-009 | 180384-43-4 | 4-(4-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-6-((5-methylpyridine)-2-sulfonamido)pyrimidin-2-yl)pyridine 1-oxide |
| CLAZ-010 | 180385-03-9 | N-(2-(2-cyanopyridin-4-yl)-6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide |
Frequently asked questions
What are the approved indications of Clazosentan Sodium?
Approved indications include: 动脉瘤, Intracranial vasospasm, Subarachnoid haemorrhage, Cerebral infarction, 脑缺血.
When does the Clazosentan Sodium patent expire?
No public expiry year is available for Clazosentan Sodium yet; this page updates once verified.
How many synthesis routes are recorded for Clazosentan Sodium?
1 synthesis routes are recorded; the shortest is 8 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Clazosentan Sodium intermediates?
All intermediates in Clazosentan Sodium routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Clazosentan Sodium intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-27