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CAS 106-93-4
1,2-dibromoethane
Codes：SITAF-015、SILO-022
Application context (from source-drug indications)
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Source drugs (routes using this intermediate)
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl 3-(3-chloro-2,4,5-trifluorophenyl)-3-oxopropanoate→(Z)-ethyl 2-(3-chloro-2,4,5-trifluorobenzoyl)-3-ethoxyacrylate→tert-butyl ((1R,2S)-2-fluorocyclopropyl)carbamate→ethyl (Z)-2-(3-chloro-2,4,5-trifluorobenzoyl)-3-(((1R,2S)-2-fluorocyclopropyl)amino)acrylate→ethyl 8-chloro-6,7-difluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate→8-chloro-6,7-difluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid→SITAF-007→7-((S)-7-((tert-butoxycarbonyl)amino)-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid→2-fluorocyclopropane-1-carboxylic acid→(R)-1-phenylethan-1-amine→2-fluoro-N-((R)-1-phenylethyl)cyclopropane-1-carboxamide→2-fluoro-N-((R)-1-phenylethyl)cyclopropane-1-carboxamide→(1S,2S)-2-fluoro-N-((R)-1-phenylethyl)cyclopropane-1-carboxamide→ethyl 3-oxobutanoate→1,2-dibromoethane→ethyl 1-acetylcyclopropane-1-carboxylate→ethyl 1-(2-bromoacetyl)cyclopropane-1-carboxylate→(R)-5-(1-phenylethyl)-5-azaspiro[2.4]heptane-4,7-dione→(R,Z)-7-(hydroxyimino)-5-(1-phenylethyl)-5-azaspiro[2.4]heptan-4-one→(S)-7-amino-5-((R)-1-phenylethyl)-5-azaspiro[2.4]heptan-4-one→(S)-5-((R)-1-phenylethyl)-5-azaspiro[2.4]heptan-7-amine→tert-butyl ((S)-5-((R)-1-phenylethyl)-5-azaspiro[2.4]heptan-7-yl)carbamate
SITAF-007→1,2-dibromoethane→benzylglycine→N-benzyl-N-(tert-butoxycarbonyl)glycine→potassium 3-ethoxy-3-oxopropanoate→ethyl 4-(benzyl(tert-butoxycarbonyl)amino)-3-oxobutanoate→ethyl 1-(N-benzyl-N-(tert-butoxycarbonyl)glycyl)cyclopropane-1-carboxylate→5-benzyl-5-azaspiro[2.4]heptane-4,7-dione→(S)-5-benzyl-7-hydroxy-5-azaspiro[2.4]heptan-4-one→(S)-5-benzyl-5-azaspiro[2.4]heptan-7-amine→tert-butyl (S)-(5-benzyl-5-azaspiro[2.4]heptan-7-yl)carbamate
1-(1-acetylindolin-5-yl)propan-1-one→1-(1-acetylindolin-5-yl)-2-bromopropan-1-one→1-(5-(2-bromopropyl)indolin-1-yl)ethan-1-one→1-(5-(2-bromopropyl)-7-nitroindolin-1-yl)ethan-1-one→1-(7-amino-5-(2-bromopropyl)indolin-1-yl)ethan-1-one→1-acetyl-5-(2-bromopropyl)indoline-7-carbonitrile→1-acetyl-5-(2-azidopropyl)indoline-7-carbonitrile→1-acetyl-5-(2-aminopropyl)indoline-7-carbonitrile→1-(2-bromoethoxy)-2-(2,2,2-trifluoroethoxy)benzene→1-acetyl-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carbonitrile→(R)-1-acetyl-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carbonitrile→tert-butyl (R)-(1-(1-acetyl-7-cyanoindolin-5-yl)propan-2-yl)(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate→tert-butyl (R)-(1-(7-cyanoindolin-5-yl)propan-2-yl)(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate→tert-butyl (R)-(1-(7-carbamoylindolin-5-yl)propan-2-yl)(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate→3-((tert-butyldimethylsilyl)oxy)propyl 4-nitrobenzenesulfonate→tert-butyl (R)-(1-(1-(3-((tert-butyldimethylsilyl)oxy)propyl)-7-carbamoylindolin-5-yl)propan-2-yl)(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate→tert-butyl (R)-(1-(7-carbamoyl-1-(3-hydroxypropyl)indolin-5-yl)propan-2-yl)(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate→2-methoxyphenol→1,1,1-trifluoro-2-iodoethane→1-methoxy-2-(2,2,2-trifluoroethoxy)benzene→2-(2,2,2-trifluoroethoxy)phenol→1,2-dibromoethane
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | Carbamic acid, (7S)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI) Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.