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CAS 1131-01-7
2-chloro-N-(2,6-dimethylphenyl)acetamide
Codes：RANO-003
Application context (from source-drug indications)
心绞痛雷诺嗪心肌梗塞雷诺嗪肌萎缩性侧索硬化雷诺嗪稳定型心绞痛雷诺嗪克罗恩病雷诺嗪炎症性肠疾病雷诺嗪
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 雷诺嗪Ranolazine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-chloroacetyl chloride→2,6-dimethylaniline→2-chloro-N-(2,6-dimethylphenyl)acetamide→piperazine→N-(2,6-dimethylphenyl)-2-(piperazin-1-yl)acetamide→2-((2-methoxyphenoxy)methyl)oxirane
2-chloro-N-(2,6-dimethylphenyl)acetamide→piperazine→2-((2-methoxyphenoxy)methyl)oxirane→2-methoxyphenol→2-(chloromethyl)oxirane→1-(2-methoxyphenoxy)-3-(piperazin-1-yl)propan-2-ol
2-chloroacetyl chloride→2,6-dimethylaniline→2-chloro-N-(2,6-dimethylphenyl)acetamide→2-((2-methoxyphenoxy)methyl)oxirane→2-methoxyphenol→2-(chloromethyl)oxirane→2,2'-azanediylbis(ethan-1-ol)→2-(bis(2-hydroxyethyl)amino)-N-(2,6-dimethylphenyl)acetamide→2-(bis(2-chloroethyl)amino)-N-(2,6-dimethylphenyl)acetamide→1-amino-3-(2-methoxyphenoxy)propan-2-ol
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