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CAS 1182314-64-2

5-(difluoromethyl)-1H-benzimidazole-2-thiol

CodesS-pantoprazole sodium-036

Application context (from source-drug indications)

胃食管反流病(S)-泮托拉唑钠消化性溃疡(S)-泮托拉唑钠出血(S)-泮托拉唑钠创伤和损伤(S)-泮托拉唑钠昏迷(S)-泮托拉唑钠吸入性肺炎(S)-泮托拉唑钠

Source drugs (routes using this intermediate)

DrugTierExpiry
(S)-泮托拉唑钠S-pantoprazole sodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

(S)-泮托拉唑钠优化路线steps: 12total yield: 61.88g(Pantoprazole (Free))
2-(chloromethyl)-3,4-dimethoxypyridine2-(3,4-dimethoxypyridin-2-yl)acetonitrilemethyl 2-(3,4-dimethoxypyridin-2-yl)acetatemethyl 2-bromo-2-(3,4-dimethoxypyridin-2-yl)acetate5-(difluoromethyl)-1H-benzimidazole-2-thiolmethyl 2-{[5-(difluoromethyl)-1H-benzimidazol-2-yl]sulfanyl}-2-(3,4-dimethoxypyridin-2-yl)acetate2-{[5-(difluoromethyl)-1H-benzimidazol-2-yl]sulfanyl}-2-(3,4-dimethoxypyridin-2-yl)acetamide2-[5-(difluoromethyl)-1H-benzimidazole-2-sulfinyl]-2-(3,4-dimethoxypyridin-2-yl)acetamide2-(3,4-dimethoxypyridin-2-yl)acetamide2-bromo-2-(3,4-dimethoxypyridin-2-yl)acetamide5-(difluoromethyl)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole

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