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CAS 169905-10-6
2-(chloromethyl)-3,4-dimethoxypyridine
Codes：S-pantoprazole sodium-004、S-pantoprazole sodium-009
Application context (from source-drug indications)
胃食管反流病（S）-泮托拉唑钠消化性溃疡（S）-泮托拉唑钠出血（S）-泮托拉唑钠创伤和损伤（S）-泮托拉唑钠昏迷（S）-泮托拉唑钠吸入性肺炎（S）-泮托拉唑钠
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| （S）-泮托拉唑钠S-pantoprazole sodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
potassium (ethoxymethanethioyl)sulfanide→1,2-Diamino-4-(difluoromethoxy)benzene→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→2-(chloromethyl)-3,4-dimethoxypyridine→5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole
2-bromo-3,4-dimethoxypyridine→3,4-dimethoxypyridine-2-carbonitrile→methyl 3,4-dimethoxypyridine-2-carboxylate→2-(chloromethyl)-3,4-dimethoxypyridine
2-(chloromethyl)-3,4-dimethoxypyridine→2-(3,4-dimethoxypyridin-2-yl)acetonitrile→methyl 2-(3,4-dimethoxypyridin-2-yl)acetate→methyl 2-bromo-2-(3,4-dimethoxypyridin-2-yl)acetate→5-(difluoromethyl)-1H-benzimidazole-2-thiol→methyl 2-{[5-(difluoromethyl)-1H-benzimidazol-2-yl]sulfanyl}-2-(3,4-dimethoxypyridin-2-yl)acetate→2-{[5-(difluoromethyl)-1H-benzimidazol-2-yl]sulfanyl}-2-(3,4-dimethoxypyridin-2-yl)acetamide→2-[5-(difluoromethyl)-1H-benzimidazole-2-sulfinyl]-2-(3,4-dimethoxypyridin-2-yl)acetamide→2-(3,4-dimethoxypyridin-2-yl)acetamide→2-bromo-2-(3,4-dimethoxypyridin-2-yl)acetamide→5-(difluoromethyl)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole
4-(Difluoromethoxy)-2-nitroaniline→1,2-Diamino-4-(difluoromethoxy)benzene→Carbon disulfide→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→2-(chloromethyl)-3,4-dimethoxypyridine→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→2-(Chloromethyl)-3,4-dimethoxy-1-oxo-1lambda5-pyridine→S-pantoprazole sodium-061
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