Unibest 优贝德
← Back to patent-cliff list

CAS 854278-84-5

2-(3,4-dimethoxypyridin-2-yl)acetonitrile

Codes:S-pantoprazole sodium-032

Application context (from source-drug indications)

胃食管反流病(S)-泮托拉唑钠消化性溃疡(S)-泮托拉唑钠出血(S)-泮托拉唑钠创伤和损伤(S)-泮托拉唑钠昏迷(S)-泮托拉唑钠吸入性肺炎(S)-泮托拉唑钠

Source drugs (routes using this intermediate)

DrugTierExpiry
(S)-泮托拉唑钠S-pantoprazole sodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

(S)-泮托拉唑钠优化路线steps: 12total yield: 61.88g(Pantoprazole (Free))
2-(chloromethyl)-3,4-dimethoxypyridine→2-(3,4-dimethoxypyridin-2-yl)acetonitrile→methyl 2-(3,4-dimethoxypyridin-2-yl)acetate→methyl 2-bromo-2-(3,4-dimethoxypyridin-2-yl)acetate→5-(difluoromethyl)-1H-benzimidazole-2-thiol→methyl 2-{[5-(difluoromethyl)-1H-benzimidazol-2-yl]sulfanyl}-2-(3,4-dimethoxypyridin-2-yl)acetate→2-{[5-(difluoromethyl)-1H-benzimidazol-2-yl]sulfanyl}-2-(3,4-dimethoxypyridin-2-yl)acetamide→2-[5-(difluoromethyl)-1H-benzimidazole-2-sulfinyl]-2-(3,4-dimethoxypyridin-2-yl)acetamide→2-(3,4-dimethoxypyridin-2-yl)acetamide→2-bromo-2-(3,4-dimethoxypyridin-2-yl)acetamide→5-(difluoromethyl)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.