CAS 3143-02-0

(3-Methyloxetan-3-yl)methanol

Codes：(II)409139-4-a

Application context (from source-drug indications)

转甲状腺素运载蛋白淀粉样变性氯苯唑酸心脏病氯苯唑酸

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
氯苯唑酸Tafamidis	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

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氯苯唑酸优化路线steps: 3total yield: /

3,5-Dichloro-1-benzenecarbonyl chloride→(3-Methyloxetan-3-yl)methanol→(3-Methyloxetan-3-yl)methyl 3,5-dichlorobenzoate→1-(3,5-Dichlorophenyl)-4-methyl-2,6,7-trioxabicyclo[2.2.2]octane→(4-Carboxy-2-hydroxyphenyl)amine→2-(3,5-Dichlorophenyl)benzo[d]oxazole-6-carboxylic acid

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