CAS 50-69-1

Codes: Molnupiravir-012, Molnupiravir-052

Application context (from source-drug indications)

COVID-19Molnupiravir呼吸道合胞体病毒感染MolnupiravirInfluenza virus infectionMolnupiravirRenal impairmentMolnupiravirHepatic function declineMolnupiravir

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Molnupiravir	Tier B — Position early	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

MolnupiravirOptimised routesteps: 12total yield: /

Molnupiravir-012→Methyl 2,3-O-isopropylidene-beta-D-ribofuranoside→Methyl 5-O-benzoyl-2,3-O-(1-methylethylidene)-beta-D-ribofuranoside→1,2,3-Tri-O-acetyl-5-O-benzoyl-beta-D-ribofuranose→2-Methylpropionyl chloride→N-(2-Oxo-1,2-dihydropyrimidin-4-yl)acetamide→N-Acetyl-2',3'-di-O-acetyl-5'-O-benzoylcytidine→Cytosine-1-beta-D-ribofuranoside→Sulfuric acid 2',3'-O-(1-methylethylidene)cytidine→2',3'-O-(1-Methylethylidene)cytidine→2',3'-O-(1-Methylethylidene)-N-(2-methylpropanoyl)-5'-O-(2-methylpropanoyl)cytidine→Hydroxylamine→Hydroxylamine hydrochloride→Hydroxylamine sulfate→N-Hydroxy-2',3'-O-(1-methylethylidene)-5'-O-(2-methylpropanoyl)cytidine→2-Methylpropionic anhydride

MolnupiravirOptimised routesteps: 3total yield: /

5-O-(2-Methylpropanoyl)-D-ribofuranose→Molnupiravir-012→alpha-Methylpropionic anhydride→2,4-Dihydroxypyrimidine→5'-O-(2-Methylpropanoyl)uridine

MolnupiravirOptimised routesteps: 5total yield: /

2,3-O-Isopropylidene-D-ribofuranose→2,3-O-(1-Methylethylidene)-1,5-bis-O-(2-methylpropanoyl)-D-ribofuranose→4-Aminopyrimidin-2(1H)-one→2',3'-O-(1-Methylethylidene)-5'-O-(2-methylpropanoyl)cytidine→Molnupiravir-052→Isobutyryl chloride

MolnupiravirOptimised routesteps: 1total yield: /

Molnupiravir-052→2,4(1H,3H)-Pyrimidinedione→1-(beta-D-Ribofuranosyl)uracil

MolnupiravirOptimised routesteps: 7total yield: 1.65g(Molnupiravir)

1,2,3-Tri-O-acetyl-5-O-(triphenylmethyl)-D-ribofuranose→2',3'-Di-O-acetyluridine→2',3'-Di-O-acetyl-5'-O-(2-methylpropanoyl)uridine→1-[2,3-Di-O-acetyl-5-O-(2-methylpropanoyl)-beta-D-ribofuranosyl]-4-[[2,4,6-tri(propan-2-yl)benzene-1-sulfonyl]oxy]pyrimidin-2(1H)-one→Molnupiravir-052→2,4(1H,3H)-Pyrimidinedione→2-Methylpropionic anhydride→Hydroxylamine hydrochloride

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

Supplier	Product	Price band	MOQ	Lead time	Qualifications	Action
Unibest Taizhou GMP-like Site	((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Pharmaceutical Intermediates	On request	On request	On request	—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.