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CAS 65-46-3
Cytosine-1-beta-D-ribofuranoside1-(beta-D-Ribofuranosyl)cytosineCytosine beta-D-riboside1-(beta-D-Ribofuranosyl)cytosine<-fgf->
Codes: Molnupiravir-019
Application context (from source-drug indications)
COVID-19Molnupiravir呼吸道合胞体病毒感染MolnupiravirInfluenza virus infectionMolnupiravirRenal impairmentMolnupiravirHepatic function declineMolnupiravir
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Molnupiravir | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Molnupiravir-012→Methyl 2,3-O-isopropylidene-beta-D-ribofuranoside→Methyl 5-O-benzoyl-2,3-O-(1-methylethylidene)-beta-D-ribofuranoside→1,2,3-Tri-O-acetyl-5-O-benzoyl-beta-D-ribofuranose→2-Methylpropionyl chloride→N-(2-Oxo-1,2-dihydropyrimidin-4-yl)acetamide→N-Acetyl-2',3'-di-O-acetyl-5'-O-benzoylcytidine→Cytosine-1-beta-D-ribofuranoside→Sulfuric acid 2',3'-O-(1-methylethylidene)cytidine→2',3'-O-(1-Methylethylidene)cytidine→2',3'-O-(1-Methylethylidene)-N-(2-methylpropanoyl)-5'-O-(2-methylpropanoyl)cytidine→Hydroxylamine→Hydroxylamine hydrochloride→Hydroxylamine sulfate→N-Hydroxy-2',3'-O-(1-methylethylidene)-5'-O-(2-methylpropanoyl)cytidine→2-Methylpropionic anhydride
Acetone oxime→2',3'-O-(1-Methylethylidene)-5'-O-(2-methylpropanoyl)cytidine→5'-O-Isobutyryl cytidine→Acetone→2-Methylpropionic acid→Sulfuric acid 2',3'-O-(1-methylethylidene)cytidine→Isobutyric anhydride→1-(beta-D-Ribofuranosyl)cytosine→Acetone O-isobutyryloxime→N-Hydroxy-2',3'-O-(1-methylethylidene)-5'-O-(2-methylpropanoyl)cytidine
Methanesulfonic acid 2',3'-O-(1-methylethylidene)cytidine (1/1)→Cytosine-1-beta-D-ribofuranoside
N-[(Dimethylamino)methylidene]cytidine→5'-O-(2-Methylpropanoyl)cytidine oxalate→N,O2',O3'-Tris[(dimethylamino)methylidene]cytidine→1-(beta-D-Ribofuranosyl)cytosine→Acetone O-isobutyryloxime→Isobutyryl chloride→2-Methylpropionic acid→5'-O-Isobutyryl cytidine→Dimethylacetic anhydride
N-[(Dimethylamino)methylidene]-2',3'-O-[(dimethylamino)methylidene]-5'-O-(2-methylpropanoyl)cytidine→N-[(Dimethylamino)methylidene]-5'-O-(2-methylpropanoyl)cytidine→N-[(Hydroxyimino)methyl]-5'-O-(2-methylpropanoyl)cytidine→Cytosine beta-D-riboside→N,O2',O3'-Tris[(dimethylamino)methylidene]cytidine→Dimethylacetic anhydride
2',3'-O-[(Dimethylamino)methylidene]-N-hydroxycytidine→2',3'-O-[(Dimethylamino)methylidene]-N-hydroxy-5'-O-(2-methylpropanoyl)cytidine→Cytosine-1-beta-D-ribofuranoside→N4-Hydroxycytidine→Isobutyric anhydride
Sulfuric acid 2',3'-O-benzylidenecytidine (1/1)→Sulfuric acid 2',3'-O-methylidenecytidine (1/1)→2',3'-O-Benzylidene-5'-O-(2-methylpropanoyl)cytidine→2',3'-O-Methylidene-5'-O-(2-methylpropanoyl)cytidine→2',3'-O-Benzylidene-N-hydroxy-5'-O-(2-methylpropanoyl)cytidine→N-Hydroxy-2',3'-O-methylidene-5'-O-(2-methylpropanoyl)cytidine→1-(beta-D-Ribofuranosyl)cytosine→2-Methylpropionic anhydride→Hydroxylamine sulfate
1-(beta-D-Ribofuranosyl)cytosine<-fgf->→N4-Hydroxycytidine→Isobutyric anhydride→5'-O-(2-Methylpropanoyl)-N-[(2-methylpropanoyl)oxy]cytidine→N-[(2-Methylpropanoyl)oxy]cytidine
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | ((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.