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CAS 7803-49-8
Amine N-oxideHydroxylamine
Codes: (XXXIV)700647-1-d, (VII)700647-4-a, Molnupiravir-023
Application context (from source-drug indications)
蠕形螨性睑缘炎Lotilaner螨虫感染Lotilaner莱姆病LotilanerRosaceaLotilaner睑板腺功能障碍LotilanerCOVID-19Molnupiravir呼吸道合胞体病毒感染MolnupiravirInfluenza virus infectionMolnupiravirRenal impairmentMolnupiravirHepatic function declineMolnupiravir
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Lotilaner | Tier C — Watch / trade | - |
| Molnupiravir | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one→2,2,2-Trifluoro-1-(3,4,5-trichlorophenyl)ethan-1-one→1-(5-Bromo-4-methylthiophen-2-yl)-4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-en-1-one→Amino alcohol hydrochloride→3-Methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophene-2-carboxylic acid→2-(5-Bromo-4-methylthiophen-2-yl)-2-methyl-1,3-dioxolane→3-Methyl-5-(2-methyl-1,3-dioxolan-2-yl)thiophene-2-carboxylic acid→Methyl 3-methyl-5-(2-methyl-1,3-dioxolan-2-yl)thiophene-2-carboxylate→Methyl 5-acetyl-3-methylthiophene-2-carboxylate→Methyl 3-methyl-5-[4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl]thiophene-2-carboxylate→Amine N-oxide→Methyl 3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophene-2-carboxylate→(5S)-3-(5-Bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazole
2,2,2-Trifluoro-1-(3,4,5-trichlorophenyl)ethan-1-one→1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one→1-(5-Bromo-4-methylthiophen-2-yl)-4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-en-1-one→3-Methyl-5-[4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl]thiophene-2-carboxylic acid→2-Amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride→3-Methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-5-[4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl]thiophene-2-carboxamide→Amine N-oxide
Molnupiravir-012→Methyl 2,3-O-isopropylidene-beta-D-ribofuranoside→Methyl 5-O-benzoyl-2,3-O-(1-methylethylidene)-beta-D-ribofuranoside→1,2,3-Tri-O-acetyl-5-O-benzoyl-beta-D-ribofuranose→2-Methylpropionyl chloride→N-(2-Oxo-1,2-dihydropyrimidin-4-yl)acetamide→N-Acetyl-2',3'-di-O-acetyl-5'-O-benzoylcytidine→Cytosine-1-beta-D-ribofuranoside→Sulfuric acid 2',3'-O-(1-methylethylidene)cytidine→2',3'-O-(1-Methylethylidene)cytidine→2',3'-O-(1-Methylethylidene)-N-(2-methylpropanoyl)-5'-O-(2-methylpropanoyl)cytidine→Hydroxylamine→Hydroxylamine hydrochloride→Hydroxylamine sulfate→N-Hydroxy-2',3'-O-(1-methylethylidene)-5'-O-(2-methylpropanoyl)cytidine→2-Methylpropionic anhydride
1-[2,3-O-(1-Methylethylidene)-5-O-(2-methylpropanoyl)-beta-D-ribofuranosyl]-4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one→1-(beta-D-Ribofuranosyl)uracil→1-[(3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione<-fgf->2',3'-O-Isopropylideneuridine→2-Methylpropionic anhydride→2',3'-O-(1-Methylethylidene)-5'-O-(2-methylpropanoyl)uridine→Hydroxylamine→N-Hydroxy-2',3'-O-(1-methylethylidene)-5'-O-(2-methylpropanoyl)cytidine
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 2-bromo-3-methyl-5-acetylthiophene Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | methyl 5-acetyl-3-methylthiophene-2-carboxylate Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 5-acetyl-3-methyl-2-Thiophenecarboxylic acid Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | ((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.