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2026-09 Patent-cliff & intermediate data digest

2026-09-19

391 patent-cliff drugs tracked (Tier A 19 / Tier B 50), 227 with recorded synthesis routes covering 4578 intermediate CAS numbers; key intermediates of 91 drugs are available through the Unibest supply network.

Core figures

391
Cliff drugs
227
Routes recorded
4578
Intermediate CAS
91
With on-sale intermediates

Tier distribution

  • Tier A · Act now19
  • Tier B · Position early50
  • Tier C · Watch / trade322

Expiry-year distribution

Expiry yearDrugs
20261
20273
202818
202920
203019
20319
20328
20332
20361

Related

Patent cliff listOncologyAnticoagulationMetabolic & GLP-1

Methodology

All figures on this page are computed at publish time by scripts/build-insights.mjs from the site's structured data (patent-cliff drug library, intermediate CAS registry, on-sale catalog). No manually filled values. Drug and CAS data are cross-verified structured fields; on-sale matching counts direct CAS listings or target-API matches.