Anticoagulation & Thrombosis
20 patent-cliff drugs in Anticoagulation & Thrombosis (classified by indication keywords and explicit molecule lists from our structured data), 15 with recorded synthesis routes and 11 with on-sale intermediates. Every "Available" badge links to real listings for RFQ.
| Drug | Tier | Expiry | Indications | Routes | CAS count | Available |
|---|---|---|---|---|---|---|
| 替格瑞洛 Ticagrelor | B · Position early | 2029 | 中风、急性冠脉综合征、心肌梗塞 | 5 | 55 | Available ×55 |
| 利伐沙班 Rivaroxaban | A · Act now | 2026 | 肺栓塞、中风、先天性心脏缺损 | 6 | 46 | Available ×46 |
| 达比加群酯甲磺酸盐 Dabigatran Etexilate Mesylate | B · Position early | - | 静脉血栓栓塞、栓塞、中风 | 7 | 31 | Available ×31 |
| 阿哌沙班 Apixaban | A · Act now | 2028 | 肺栓塞、静脉血栓形成、Paget-Schroetter综合征 | 7 | 30 | Available ×30 |
| 坎格雷洛四钠盐 Cangrelor Tetrasodium | C · Watch | - | 冠状动脉血栓、心肌梗塞、血栓形成 | 2 | 21 | Available ×21 |
| 马来酸阿伐曲泊帕 Avatrombopag Maleate | C · Watch | 2030 | 血小板减少、特发性血小板减少性紫癜、肝脏疾病 | 1 | 11 | Available ×11 |
| 福他替尼二钠六水合物 Fostamatinib disodium hexahydrate | C · Watch | - | 特发性血小板减少性紫癜、血小板减少 | 1 | 6 | Available ×6 |
| 甲苯磺酸艾多沙班 Edoxaban Tosilate Hydrate | B · Position early | 2028 | 肺栓塞、静脉血栓栓塞、中风 | 6 | 37 | Available ×3 |
| 马昔腾坦 Macitentan | B · Position early | - | 肺动脉高压 | 2 | 18 | Available ×1 |
| 芦曲泊帕 Lusutrombopag | C · Watch | 2031 | 血小板减少 | 1 | 12 | Available ×1 |
| 西达本胺 Chidamide | C · Watch | - | 弥漫性大B-细胞淋巴瘤、T-细胞白血病、乳腺癌 | 1 | 6 | Available ×1 |
| 贝曲沙班 Betrixaban | C · Watch | 2028 | 静脉血栓栓塞、肝功能衰退、心房颤动 | 2 | 10 | - |
| 乳酸帕比司他 Panobinostat Lactate | C · Watch | - | 多发性骨髓瘤 | 2 | 11 | - |
| Fedratinib Fedratinib | C · Watch | - | 骨髓纤维化、脾大 | 1 | 4 | - |
| 利奥西呱 Riociguat | B · Position early | - | 肺动脉高压、肺性高血压、慢性血栓栓塞性肺高压 | 1 | 10 | - |
| Defibrotide sodium Defibrotide sodium | C · Watch | - | 肝静脉阻塞病 | - | - | - |
| 雷贝拉唑钠/甲硝唑/阿莫西林 Rabeprazole Sodium/Metronidazole/Amoxicillin | C · Watch | - | 十二指肠溃疡、特发性血小板减少性紫癜、胃溃疡 | - | - | - |
| 克拉霉素/雷贝拉唑钠/阿莫西林 Clarithromycin/Rabeprazole Sodium/Amoxicillin | C · Watch | - | 边缘带B细胞淋巴瘤、十二指肠溃疡、特发性血小板减少性紫癜 | - | - | - |
| 盐酸噻氯匹定/银杏叶提取物 Ticlopidine Hydrochloride/Ginkgo Biloba Leaf Dried Extract | C · Watch | - | 动脉闭塞性疾病、脑血管疾病、栓塞和血栓形成 | - | - | - |
| 硫酸氢氯吡格雷/阿司匹林 Clopidogrel Bisulfate/Aspirin | C · Watch | - | 动脉粥样硬化、急性冠脉综合征、血栓形成 | - | - | - |
Frequently asked questions
Which patent-cliff drugs in Anticoagulation & Thrombosis are worth tracking?
20 drugs related to Anticoagulation & Thrombosis are tracked on this site, 15 of them with recorded synthesis routes. See the table above and open each drug profile for routes and intermediates.
Where can I source Anticoagulation & Thrombosis intermediates?
Key intermediates of 11 drugs in this table are available through the Unibest supply network; for the rest, submit an RFQ per CAS on the intermediate profile pages.
Where can I check patent expiry for these drugs?
Each drug profile shows the public expiry year; yearly overviews are available at /patent-cliff/expires/<year>.
Source: cross-verified structured fields · Classification: indication keywords + explicit molecule lists · 2026-09-24