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CAS 229613-93-8
methyl (3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylate
Codes：PERA-005
Application context (from source-drug indications)
流感病毒感染帕拉米韦甲型流感病毒感染帕拉米韦乙型流感病毒感染帕拉米韦鼻塞帕拉米韦发热帕拉米韦咳嗽帕拉米韦
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 帕拉米韦Peramivir Hydrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one→methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate→methyl (1S,4R)-4-((tert-butoxycarbonyl)amino)cyclopent-2-ene-1-carboxylate→3-(nitromethyl)pentane→methyl (3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylate→methyl (1S,2S,3S,4R)-3-((S)-1-amino-2-ethylbutyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentane-1-carboxylate→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentane-1-carboxylate→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-amino-2-hydroxycyclopentane-1-carboxylate→1H-pyrazole-1-carboximidamide hydrochloride
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one→methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate→methyl (1S,4R)-4-((tert-butoxycarbonyl)amino)cyclopent-2-ene-1-carboxylate→methyl (3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylate→methyl (1S,2S,3S,4R)-3-((S)-1-amino-2-ethylbutyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentane-1-carboxylate→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentane-1-carboxylate→(E)-2-ethylbutanal oxime→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-amino-2-hydroxycyclopentane-1-carboxylate hydrochloride→carbamimidic chloride hydrochloride
methyl (1S,4R)-4-((tert-butoxycarbonyl)amino)cyclopent-2-ene-1-carboxylate→methyl (3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylate→2-azabicyclo[2.2.1]hept-5-en-3-one→methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate (2R,3R)-2,3-dihydroxysuccinate→(Z)-2-ethyl-N-hydroxybutanimidoyl chloride→(3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylic acid→methyl (1S,2S,3S,4R)-3-((S)-1-aminoethyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentane-1-carboxylate
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one→methyl (1S,4R)-4-((tert-butoxycarbonyl)amino)cyclopent-2-ene-1-carboxylate→3-(nitromethyl)pentane→methyl (3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylate→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentane-1-carboxylate→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-amino-2-hydroxycyclopentane-1-carboxylate→ tert-butyl N-[[(2-methylpropan-2-yl)oxycarbonylamino]-methylsulfanylmethylidene]carbamate→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)-2-hydroxycyclopentane-1-carboxylate→(1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)-2-hydroxycyclopentane-1-carboxylic acid
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | (3aR,4R,6S,6aS)-4-[[(1,1-DiMethylethoxy)carbonyl]aMino]-3-(1-ethylpropyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazole-6-carboxylic Acid Methyl Ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
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