← Back to patent-cliff list
CAS 419563-22-7
methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate (2R,3R)-2,3-dihydroxysuccinate
Codes：PERA-014
Application context (from source-drug indications)
流感病毒感染帕拉米韦甲型流感病毒感染帕拉米韦乙型流感病毒感染帕拉米韦鼻塞帕拉米韦发热帕拉米韦咳嗽帕拉米韦
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 帕拉米韦Peramivir Hydrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
methyl (1S,4R)-4-((tert-butoxycarbonyl)amino)cyclopent-2-ene-1-carboxylate→methyl (3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylate→2-azabicyclo[2.2.1]hept-5-en-3-one→methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate (2R,3R)-2,3-dihydroxysuccinate→(Z)-2-ethyl-N-hydroxybutanimidoyl chloride→(3aR,4R,6S,6aS)-4-((tert-butoxycarbonyl)amino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylic acid→methyl (1S,2S,3S,4R)-3-((S)-1-aminoethyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentane-1-carboxylate
methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate (2R,3R)-2,3-dihydroxysuccinate→(Z)-2-ethyl-N-hydroxybutanimidoyl chloride→methyl (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)-2-hydroxycyclopentane-1-carboxylate→(1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)-2-hydroxycyclopentane-1-carboxylic acid→(3R,3'R)-di-tert-butyl 3,3'-((((pyrimidine-4,6-dicarbonyl)bis(azanediyl))bis(2-(5-aminopentanamido)-4-(trifluoromethyl)-6,1-phenylene))bis(oxy))bis(pyrrolidine-1-carboxylate)→methyl (1S,4R)-4-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)cyclopent-2-ene-1-carboxylate→methyl (3aR,4R,6S,6aS)-4-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)-3-(pentan-3-yl)-3a,5,6,6a-tetrahydro-4H-cyclopenta[d]isoxazole-6-carboxylate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.