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CAS 105-34-0

methyl 2-cyanoacetate2-Cyanoacetic acid methyl ester

CodesROXA-015、Cefoselis Sulfate-011

Application context (from source-drug indications)

贫血罗沙司他细菌感染硫酸头孢噻利

Source drugs (routes using this intermediate)

DrugTierExpiry
罗沙司他RoxadustatTier C — Watch / trade2028
硫酸头孢噻利Cefoselis SulfateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

硫酸头孢噻利优化路线steps: 10total yield: 231. 2g(Cefoselis Sulfate-001)
2-(5-Amino-1H-pyrazol-1-yl)ethan-1-olN,N-Dimethylformamide2-Cyanoacetic acid methyl ester2-Cyanoacetic acid ethyl esterPropyl cyanoacetateButyl cyanoacetateMethyl 2-cyano-3-(dimethylamino)prop-2-enoateEthyl 2-cyano-3-(dimethylamino)prop-2-enoatePropyl 2-cyano-3-(dimethylamino)prop-2-enoateButyl 2-cyano-3-(dimethylamino)prop-2-enoate2-HydrazinoethanolMethyl 5-amino-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxylateEthyl 5-amino-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxylatePropyl 5-amino-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxylateButyl 5-amino-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxylate5-Amino-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxylic acidHex-3-enedinitrileBut-3-enenitrile3-Oxopropanenitrile3,3-Dimethoxypropanenitrile3-[2-(2-Hydroxyethyl)hydrazinylidene]propanenitrile

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

SupplierProductPrice bandMOQLead timeQualifications
Unibest Taizhou GMP-like Site4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid
Pharmaceutical Intermediates
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Qualified Partner — East China API Works4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid
Pharmaceutical Intermediates
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Unibest Nantong cGMP SiteMethyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
Pharmaceutical Intermediates
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Unibest Taizhou GMP-like Site5-Phenoxyisobenzofuran-1(3H)-one
Pharmaceutical Intermediates
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Qualified Partner — East China API Works4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid ethyl ester
Pharmaceutical Intermediates
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Unibest Nantong cGMP Site4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester
Pharmaceutical Intermediates
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.