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CAS 172282-50-7
1,2-Diamino-4-(difluoromethoxy)benzene
Codes：S-pantoprazole sodium-002
Application context (from source-drug indications)
胃食管反流病（S）-泮托拉唑钠消化性溃疡（S）-泮托拉唑钠出血（S）-泮托拉唑钠创伤和损伤（S）-泮托拉唑钠昏迷（S）-泮托拉唑钠吸入性肺炎（S）-泮托拉唑钠
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| （S）-泮托拉唑钠S-pantoprazole sodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
potassium (ethoxymethanethioyl)sulfanide→1,2-Diamino-4-(difluoromethoxy)benzene→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→2-(chloromethyl)-3,4-dimethoxypyridine→5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole
4-Acetamidophenol→Chlorodifluoromethane→N-[4-(Difluoromethoxy)phenyl]acetamide→N-[4-(Difluoromethoxy)-2-nitrophenyl]acetamide→2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→4-(Difluoromethoxy)-2-nitroaniline→1,2-Diamino-4-(difluoromethoxy)benzene→O-Ethylxanthic acid potassium salt→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→(3,4-Dimethoxypyridin-2-yl)methanol
2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→Aminothiocarboxamide→(3,4-Dimethoxypyridin-2-yl)methyl hydrosulfide→Chloridocarbonic acid ethyl ester→Ethyl (3,4-dimethoxy-2-pyridyl)methylsulfanylformate→1,2-Diamino-4-(difluoromethoxy)benzene→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfinyl)-1H-benzimidazole
4-(Difluoromethoxy)-2-nitroaniline→1,2-Diamino-4-(difluoromethoxy)benzene→Carbon disulfide→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→2-(chloromethyl)-3,4-dimethoxypyridine→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→2-(Chloromethyl)-3,4-dimethoxy-1-oxo-1lambda5-pyridine→S-pantoprazole sodium-061
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